Biography
Education
- 1978 — A.B., Physics, magna cum laude, Harvard College
- 1981 — Ph.D., Molecular Biology, University of California at Los Angeles
Professional Experience
- 1978–1981 — National Science Foundation Predoctoral Fellow with Prof. David Eisenberg, UCLA
- 1982–1985 — Helen Hay Whitney Postdoctoral Fellow with Prof. D. E. Koshland, Jr., UC-Berkeley
- 1985–1991 — Assistant Professor of Biochemistry and Molecular Biology, University of Chicago
- 1992–2001 — Technical Staff Member, Los Alamos National Laboratory
- 2001–present — Laboratory Fellow, Los Alamos National Laboratory (retired 2017)
- 2017–present — Senior Scientist, New Mexico Consortium
Honors & Awards
- Bronze Award, Michigan Mathematics Prize Competition (1976)
- Harvard Scholarship (1976)
- NSF Graduate Fellowship (1978–1981)
- Helen Hay Whitney Postdoctoral Fellowship (1982–1985)
- Presidential Young Investigator Award (1985–1990)
- R&D 100 Award (1998)
- Los Alamos Distinguished Copyright Award (1999)
- AAAS Fellow (2000)
- Los Alamos Platinum Licensing Award (2001)
- Los Alamos National Laboratory Fellow (2001)
- Los Alamos Distinguished Patent Award (2004)
- Federal Laboratory Consortium Award for Excellence in Technology Transfer (2005)
- Fellow, American Crystallographic Association (2012)
- Trueblood Award, American Crystallographic Association (2013)
- Member, National Academy of Sciences (2025)
Professional Service
Chair, Biosciences Committee of the Los Alamos Laboratory-Directed Research and Development Program (1997–1999). Los Alamos National Laboratory Directed Research Strategy Team (1999–2002). NRC U.S. National Committee on Crystallography (1999). Editorial Advisory Board, Protein Science (1997–2002). NASA Panel on Protein Crystal Growth (1996–2001). NIH Macromolecular Structure and Function Study Section (2002–2006). Reviewer for the National Science Foundation, UK Biotechnology and Biological Sciences Research Council, European Commission Fundamental Genomics, and the Wellcome Trust.
Organizer, Workshop on Structural Genomics (Argonne National Laboratory, 1998). Chair, 2004 Gordon Research Conference on Diffraction Methods in Structural Biology. Los Alamos Science Council (2004–2007). Organizer and member of Executive Committee, International Structural Genomics Organization (2000–2008). Leader, TB Structural Genomics Consortium (2000–2005).
Co-editor, Acta Crystallographica section F (2005–2017). Co-editor, Journal of Structural and Functional Genomics (2005–2016). Reviewer for Science, Nature, Nature Methods, Nature Structural Biology, Proceedings of the National Academy of Sciences, Biochemistry, Journal of Biological Chemistry, Journal of Molecular Biology, Journal of Structural and Functional Genomics, Proteins.
Scientific Committee, Structural Genomics Consortium (2003–2015). Advisory Panel, Structural Genomics of Pathogenic Protozoa (2001–2005). Advisory Panel, SBGrid (2015–2026). Advisory Panel, Center for Structural Genomics of Infectious Diseases (2008–2017). Commission on Biological Macromolecules, International Union of Crystallography (2008–2017; chair 2015–2017). IUCR Diffraction Data Deposition Working Group (2011–2017).
American Crystallographic Association: Vice-President (2015), President (2016), Past President (2017).